04 Sedation
- related: ICU
- tags: #icu
- analgesics (pain) vs anxiolytics (sedation)
- IV push vs drip
- RASS goal? Stay in 0, -1, -2
Anxiolytics
| Push | Drip | Dosing | Indication | Caution | |
|---|---|---|---|---|---|
| Propofol | xx | 0.5 mcg/kg/min 0-100mg |
- drug of choice - fat soluble - short half life |
-hypotension>bradycardia - propofol infusion syndrome - hyperlipidemia |
|
| Versed midazolam |
xx | xx | 0.04 mg/kg/hr | - sedation - ETOH withdrawal on vent - seizures |
- hypotension - delirium - accumulation in fatty tissues - liver renal dosing |
| Ativan Lorazepam |
xx | 0.04 mg/kg/hr 1-4mg IV Q3 PRN |
- ETOH withdrawal - seizures - CIWA |
- same as Versed - propylene glycol toxicity (no drip) |
|
| Halodol | xx | 5-10mg IV Q4-6 PRN | - delirium - agitation |
- long QT - EPS |
|
| Precedex Dexmedotramidin |
xx | 0-0.7 mcg/kg/hr | - delirium - agitation - weaning off vent |
- bradycardia>hypotension - cost |
|
| Ketamine | xx | only status epilepticus |
Analgesics
| Push | Drip | Dosing | Indication | Caution | |
|---|---|---|---|---|---|
| Fentanyl | xx | xx | 25-100 IV PRN Q2 0.1-4 mcg/kg/hr |
- drug of choice - short 1/2 life - BP neutral |
safe short 1/2 life |
| Dilaudid | xx | x | 0.5-4 mg Q3 | - opioid experienced - sickle cell |
hypotension |
| Morphine | xx | 5-10 mg IV Q3 | - rarely in ICU - terminal weaning - air hunger suppression |
hypotension histamine release itching renal failure |